Immunological Studies on Human Saliva

Studies of Human Mixed Saliva

In 1835, Donne (1) reported that although he found the saliva normally alkaline to litmus, he had found it acid in many diseases, including encephalitis. In 1844, Wright (2) attempted to elaborate a diagnostic system of salivary analysis. About the same time, Simon (3) wrote at length on “morbid saliva” as distinct from “normal.” Among other studies of a similar character were those of Binet (4...

Studies on the Antibacterial Factors of Human Saliva.

In previous studies it was found that the growth of 110 of 169 strains of bacteria tested was prevented by human saliva (Bibby, Clough and Hine, 1938). This effect was more marked against some types of organisms than against others, those most affected being bacilli and cocci isolated from air and water; those least affected, organisms isolated from the mouth. Differences occurred in the inhibi...

[Immunological studies on cryoglobulin].

Subacute Sclerosing Panencephalitis, immunological findings in saliva and salivary glands

Immunological Studies of Human Γ-globulin

Two major antigenic fragments were obtained from various purified gamma-globulin preparations after papain treatment. One, the F component, had a mobility faster than the original gamma-globulin and the second, the S component, had a slower mobility. Similar F and S components were also obtained with certain homogeneous myeloma proteins which were closely related to gamma-globulin immunological...